Enteroendocrine cells couple nutrient sensing to nutrient absorption by regulating ion transport
نویسندگان
چکیده
منابع مشابه
Intestinal organoids for assessing nutrient transport, sensing and incretin secretion
Intestinal nutrient transport and sensing are of emerging interest in research on obesity and diabetes and as drug targets. Appropriate in vitro models are lacking that allow both, studies on transport processes as well as sensing and subsequent incretin hormone secretion including intracellular signaling. We here demonstrate that murine small-intestinal organoids are the first in vitro model s...
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ژورنال
عنوان ژورنال: Nature Communications
سال: 2020
ISSN: 2041-1723
DOI: 10.1038/s41467-020-18536-z